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17 May 2017, 10:02 am
Douglas McDaniel (1920 - 2008)Honorable David G. [read post]
12 Dec 2021, 2:22 pm by admin
The late Douglas Altman, who did so much to steer the medical literature toward greater validity, warned that dichotomizing continuous variables was known to cause loss of information, statistical power, and reliability in medical research.[17] In the field of pharmaco-epidemiology, the bias created by dichotomization of a continous variable is harmful from both the perspective of statistical estimation and hypothesis testing.[18] While readers are misled into believing that the study… [read post]